DNA Recombination and Repair

Plant DNA repair and recombination on the French Mediterranean. Workshop on plant DNA repair & recombination.

Genetic recombination as DNA repair

Maintenance of sexual reproduction and genetic recombination imposes physiological costs when compared to parthenogenic reproduction, most prominently: for maintaining the corresponding (molecular) machinery, for finding a mating partner, and through the decreased fraction of females in a population, which decreases the reproductive capacity. Based on principles from information theory, we have...

Genome Stability: DNA Repair and Recombination

Gene Control, second edition, is a concise book that focuses on gene expression and regulation in eukaryotes. Synonymous with the first edition, the chapters build on themselves, culminating in a discussion correlating gene control in regard to human health and disease. The author uses illustrations where appropriate, focusing on simplistic figures that correlate DNA, RNA, and regulatory protei...

DNA in 3R: Repair, Replication, and Recombination

This special issue entitled “DNA in 3R: Repair, Replication, and Recombination” is dedicated to biological processes that preserve the integrity of our genome. These phenomena have attracted broad interest among a large community of scientists that cross disciplines from mathematics, physics, chemistry, and biology to clinical scientists. DNA is continuously exposed to a range of damaging agent...

Repair and recombination induced by triple helix DNA.

Triple-helix DNA structures can form endogenously at mirror repeat polypurine/polypyrimidine sequences or by introduction of triplex-forming oligonucleotides (TFOs). Recent evidence suggests that triple helices are sources of genetic instability, and are subject to increased rates of mutagenesis and recruitment of repair factors. Indeed, observations using TFOs suggest that triple helices provo...